| Variable | Response |
|---|---|
| Full Name | Singapore Longitudinal Ageing Studies |
| CRS Continent(s) | Africa |
| CRS ID | 119 |
| Acronym | SLAS I&II |
| Low-Middle Income Country | No |
| Data Available Through DPAU | No |
| Follow-Up Data Available | Yes |
| CRS Overview | The establishment of the Singapore Longitudinal Aging Cohort will provide a large community-based cohort of elderly subjects for observational studies with useful clinical applications. Research synergy is achieved in terms of pooling multi-disciplinary expertise, and combining genetic, biological, environmental, behavioural, social, clinical, and health services approaches to gerontological research. |
| No. of Subjects at Baseline | 2800 |
| Institution | National University, Singapore |
| Department Name | Yong Loo Lin School of Medicine,; Department of Psychological Medicine |
| City | Singapore |
| Country | Singapore |
| Study/Database Website | https://clinicaltrials.gov/ct2/show/NCT03405675 |
| Principal Investigator (PI) | Ng Tze Pin |
| PI email | pcmngtp@nus.edu.sg |
| Key Study References | SLAS-I: Niti M, Yap KB, Kua EH, Tan CH, Ng TP. Physical, social and productive leisure activities, cognitive decline and interaction with APOE-epsilon4 genotype in Chinese older adults. Int Psychogeriatr. 2008 Jan 11:1-15.; SLAS-II: Feng L, Chong MS, Lim WS, Lee TS,Collinson SL, Yap P, Ng TP. Metabolic syndrome (MetS) and amnestic mild cognitive impairment (aMCI): Singapore Longitudinal Ageing Studies-2 Findings. J Alzheimers Dis. 2013 Jan 1;34(3):649-57. |
| Population Based Study? | Yes |
| Family Based Study? | No |
| Clinical Based Sample? | No |
| Were participants included prior to development of dementia (may refer to controls only)? | Yes |
| Were participants included prior to development of MCI (may refer to controls only)? | Yes |
| How is data collected? | face-to-face |
| Who carries out data collection? | trained research nurses, research assistants, and research fellows with medical and psychology backgrounds.; psychologists trained by a clinical neuropsychologist |
| Does this take place in participants' homes or at a central location? | home and local testing sites |
| Do participants take part individually or are families/partners involved? | Individually |
| Dementia cases ascertained as part of study | Yes |
| Diagnosis based on review of existing clinical data | No |
| Were diagnosis/primary outcomes made blind to exposure variables? | Not Applicable |
| How many times followed up? | 2 |
| Sample Size at Follow-Up | 1850 (SLAS-1) 1458 (SLAS-2) |
| Study start date | 2003 |
| Study end date | 0 |
| Study Timeline | Baseline: 2003-2004 (SLAS-1) 2009-2011 (SLAS-2) followed up at approximately 3-4 year intervals in the SLAS-1 cohort, and 3 to 5-years interval in the SLAS-2 cohort. |
| Is data collection still ongoing? | Yes |
| Is study still recruiting? | No |
| Inclusion criteria | Ability to self-ambulate and adequate cognitive capacity for participation |
| Exclusion criteria | Advanced disability, terminal chronic illnss, profiund cogntive impairment (dementia) |
| Minimum Age | 55 |
| Sex Included in Study | Male and Female |
| Are there likely to be updates or revisions to the data after its release? | No |
| Notes | NCT03405675 |
| Publications | |
| Documents | |
| Data Availability | Data not available on DPAU |
| Data Access Process | Direct application to CRS |
| Data Distribution Rule | Not distributed via DPAU |
We are still preparing the information for this section. Please come again later.