| Variable | Response |
|---|---|
| Full Name | Leipzig Longitudinal Study of the Aged |
| CRS Continents(s) | Europe |
| CRS ID | 104 |
| Acronym | LEILA75+ |
| Low-Middle Income Country | No |
| Data Available Through DPAU | Yes |
| Follow-Up Data Available | Yes |
| CRS Overview | LEILA75+ is a prospective population-based cohort study on the epidemiology of dementia and mild cognitive impairment (MCI). The aims of the study are to determine the prevalence and incidence of dementia and of MCI, as well as the occurrence of related conditions such as subjective cognitive decline, and to identify their risk factors. |
| No. of Subjects at Baseline | 1265 |
| Institution | University of Leipzig |
| Department Name | Institute of Social Medicine, Occupational Health and Public Health (ISAP) |
| City | Leipzig |
| Country | Germany |
| Study/Database Website | http://isap.uniklinikum-leipzig.de |
| Principal Investigator (PI) | Prof. Dr. med. Steffi G. Riedel-Heller, MPH |
| PI email | steffi.riedel-heller@medizin.uni-leipzig.de |
| Key Study References | Riedel-Heller, S.G., Busse, A., Aurich, C., Matschinger, H., Angermeyer, M.C. Prevalence of dementia according to DSM-III-R and ICD-10. Results of the Leipzig Longitudinal Study of the Aged (LEILA75+) Part I. British Journal of Psychiatry (2001) 179, 250-254; Riedel-Heller, S. G., Busse, A., Aurich, C., Matschinger, H., & Angermeyer, M. C. Incidence of dementia according to DSM-III-R and ICD-10: results of the Leipzig Longitudinal Study of the Aged (LEILA75+), Part 2. British jourJnal of Psychiatry (2001) 179, 255-260. |
| Population Based Study? | Yes |
| Family Based Study? | No |
| Clinical Based Sample? | No |
| Were participants included prior to development of dementia (may refer to controls only)? | No |
| Were participants included prior to development of MCI (may refer to controls only)? | No |
| How is data collected? | Face-to-face |
| Who carries out data collection? | trained physicians and psychologists |
| Does this take place in participants' homes or at a central location? | home visit |
| Do participants take part individually or are families/partners involved? | informant involved |
| Dementia cases ascertained as part of study | Yes |
| Diagnosis based on review of existing clinical data | No |
| Were diagnosis/primary outcomes made blind to exposure variables? | Not Applicable |
| How many times followed up? | 6 |
| Sample Size at Follow-Up | Baseline: 1,265 participants Follow-up 1: 742 participants Follow-up 2: 610 participants Follow-up 3: 483 participants Follow-up 4: 375 participants Follow-up 5: 313 participants Follow-up 6: 181 participants |
| Study start date | 1997 |
| Study end date | 2014 |
| Study Timeline | Five follow-up assessments scheduled every 18 months. A final long-term follow-up was conducted 8 years after follow-up 5, for a total observation period of 16 years. |
| Is data collection still ongoing? | No |
| Is study still recruiting? | No |
| Inclusion criteria | Aged 75 and over |
| Exclusion criteria | |
| Minimum Age | 75 |
| Sex Included in Study | Male and Female |
| Are there likely to be updates or revisions to the data after its release? | No |
| Notes | Not applicable |
| Publications |
|
| Documents | |
| Data Availability | Data not available on DPAU |
| Data Access Process | Direct application to CRS |
| Data Distribution Rule | Not distributed via DPAU |
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