Leipzig Longitudinal Study of the Aged
University of Leipzig


Variable Response
Full Name Leipzig Longitudinal Study of the Aged
CRS Continents(s) Europe
CRS ID 104
Acronym LEILA75+
Low-Middle Income Country No
Data Available Through DPAU Yes
Follow-Up Data Available Yes
CRS Overview LEILA75+ is a prospective population-based cohort study on the epidemiology of dementia and mild cognitive impairment (MCI). The aims of the study are to determine the prevalence and incidence of dementia and of MCI, as well as the occurrence of related conditions such as subjective cognitive decline, and to identify their risk factors.
No. of Subjects at Baseline 1265
Institution University of Leipzig
Department Name Institute of Social Medicine, Occupational Health and Public Health (ISAP)
City Leipzig
Country Germany
Study/Database Website http://isap.uniklinikum-leipzig.de
Principal Investigator (PI) Prof. Dr. med. Steffi G. Riedel-Heller, MPH
PI email steffi.riedel-heller@medizin.uni-leipzig.de
Key Study References Riedel-Heller, S.G., Busse, A., Aurich, C., Matschinger, H., Angermeyer, M.C. Prevalence of dementia according to DSM-III-R and ICD-10. Results of the Leipzig Longitudinal Study of the Aged (LEILA75+) Part I. British Journal of Psychiatry (2001) 179, 250-254; Riedel-Heller, S. G., Busse, A., Aurich, C., Matschinger, H., & Angermeyer, M. C. Incidence of dementia according to DSM-III-R and ICD-10: results of the Leipzig Longitudinal Study of the Aged (LEILA75+), Part 2. British jourJnal of Psychiatry (2001) 179, 255-260.
Population Based Study? Yes
Family Based Study? No
Clinical Based Sample? No
Were participants included prior to development of dementia (may refer to controls only)? No
Were participants included prior to development of MCI (may refer to controls only)? No
How is data collected? Face-to-face
Who carries out data collection? trained physicians and psychologists
Does this take place in participants' homes or at a central location? home visit
Do participants take part individually or are families/partners involved? informant involved
Dementia cases ascertained as part of study Yes
Diagnosis based on review of existing clinical data No
Were diagnosis/primary outcomes made blind to exposure variables? Not Applicable
How many times followed up? 6
Sample Size at Follow-Up Baseline: 1,265 participants
Follow-up 1: 742 participants
Follow-up 2: 610 participants
Follow-up 3: 483 participants
Follow-up 4: 375 participants
Follow-up 5: 313 participants
Follow-up 6: 181 participants
Study start date 1997
Study end date 2014
Study Timeline Five follow-up assessments scheduled every 18 months. A final long-term follow-up was conducted 8 years after follow-up 5, for a total observation period of 16 years.
Is data collection sill ongoing? No
Is study still recruiting? No
Inclusion criteria Aged 75 and over
Exclusion criteria
Minimum Age 75
Sex Included in Study Male and Female
Are there likely to be updates or revisions to the data after its release? No
Notes Not applicable
Publications
Documents
Data Availability Data not available on DPAU
Data Access Process Direct application to CRS
Data Distribution Rule Not distributed via DPAU

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